Version 5.4
Homo sapiens Gene: UBE3C
Summary
InnateDB Gene IDBG-50773.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE3C
Gene Name ubiquitin protein ligase E3C
Synonyms HECTH2
Species Homo sapiens
Ensembl Gene ENSG00000009335
Encoded Proteins
IDBP-50775
ubiquitin protein ligase E3C
IDBP-50781
ubiquitin protein ligase E3C
IDBP-387585
ubiquitin protein ligase E3C
IDBP-808326
ubiquitin protein ligase E3C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:157138913-157269372
Strand Forward strand
Band q36.3
Transcripts
ENST00000348165 ENSP00000309198
ENST00000389103 ENSP00000373755
ENST00000430750 ENSP00000397432
ENST00000469336
ENST00000470408
ENST00000497368
ENST00000494532
ENST00000474153
ENST00000611269 ENSP00000481584
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 34 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0000209 protein polyubiquitination
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039000
View Gene Order
ENSBTAG00000008025
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.118351 Hs.605244 Hs.711323
RefSeq NM_014671 XM_005249564
HUGO
OMIM
CCDS CCDS34789
HPRD 15604
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca