Version 5.4
| Homo sapiens Gene: SCGB1D2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-50897.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | SCGB1D2 | ||||||||||||||||||
| Gene Name | secretoglobin, family 1D, member 2 | ||||||||||||||||||
| Synonyms | LIPB; LPHB; LPNB | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000124935 | ||||||||||||||||||
| Encoded Proteins |
secretoglobin, family 1D, member 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:62242210-62244808 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q12.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O95969 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 10647 | ||||||||||||||||||
| UniGene | Hs.204096 | ||||||||||||||||||
| RefSeq | NM_006551 XM_006718422 | ||||||||||||||||||
| HUGO | HGNC:18396 | ||||||||||||||||||
| OMIM | 615061 | ||||||||||||||||||
| CCDS | CCDS8017 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AJ224172 BC069290 BC104838 BC104840 | ||||||||||||||||||
| GenPept | AAH69290 AAI04839 AAI04841 CAA11864 | ||||||||||||||||||
| RNA Seq Atlas | 10647 | ||||||||||||||||||