Version 5.4
Homo sapiens Gene: ZNF645
Summary
InnateDB Gene IDBG-51924.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF645
Gene Name zinc finger protein 645
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000175809
Encoded Proteins
IDBP-51928
zinc finger protein 645
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the zinc finger domain-containing protein family. This family member contains both a RING-type and a C2H2-type of zinc finger domain, and it may function as an E3 ubiquitin-protein ligase. Protein localization suggests a role in human sperm production and quality control. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:22272943-22274457
Strand Forward strand
Band p22.11
Transcripts
ENST00000323684 ENSP00000323348
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8N7E2
TrEMBL
UniProt Splice Variant
Entrez Gene 158506
UniGene Hs.132485
RefSeq NM_152577
HUGO HGNC:26371
OMIM
CCDS CCDS14205
HPRD
IMGT
EMBL AK098601 BC074910 BC126190 BC126192 BX293560
GenPept AAH74910 AAI26191 AAI26193 BAC05348 CAI40652
RNA Seq Atlas 158506

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca