InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL27

Summary

InnateDB Gene

IDBG-52040.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL27

Gene Name

ribosomal protein L27

Synonyms

L27

Species

Homo sapiens

Ensembl Gene

ENSG00000131469

Encoded Proteins

IDBP-52042

ribosomal protein L27

IDBP-761193

IDBP-762724

IDBP-759929

IDBP-764688

IDBP-763933

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:42998273-43002959

Strand

Forward strand

Band

q21.31

Transcripts

ENST00000253788	ENSP00000253788
ENST00000589913	ENSP00000464813
ENST00000586277	ENSP00000466019
ENST00000589037	ENSP00000467587
ENST00000587478
ENST00000590864	ENSP00000467939
ENST00000593262
ENST00000588830	ENSP00000468468

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 76 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	76 [view]
Protein-Protein	73 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome