Version 5.4
Homo sapiens Gene: CELF2
Summary
InnateDB Gene IDBG-52770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CELF2
Gene Name CUGBP, Elav-like family member 2
Synonyms BRUNOL3; CUGBP2; ETR-3; ETR3; NAPOR
Species Homo sapiens
Ensembl Gene ENSG00000048740
Encoded Proteins
IDBP-52774
CUGBP, Elav-like family member 2
IDBP-229627
CUGBP, Elav-like family member 2
IDBP-365280
CUGBP, Elav-like family member 2
IDBP-365284
CUGBP, Elav-like family member 2
IDBP-589995
CUGBP, Elav-like family member 2
IDBP-812078
CUGBP, Elav-like family member 2
IDBP-812079
CUGBP, Elav-like family member 2
IDBP-812080
CUGBP, Elav-like family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:11005296-11336675
Strand Forward strand
Band p14
Transcripts
ENST00000354897 ENSP00000346971
ENST00000399850 ENSP00000382743
ENST00000417956 ENSP00000404834
ENST00000416382 ENSP00000406451
ENST00000542579 ENSP00000443926
ENST00000608830 ENSP00000476999
ENST00000609870 ENSP00000476392
ENST00000609692 ENSP00000476656
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006376 mRNA splice site selection
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008016 regulation of heart contraction
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000002107
View Gene Order
Cross-References
SwissProt O95319
TrEMBL B4DT00 B4DZ01
UniProt Splice Variant
Entrez Gene 10659
UniGene Hs.309288 Hs.608140 Hs.617569 Hs.620907
RefSeq NM_001025077 XM_005252357 NM_001025076 NM_001083591 NM_006561 XM_005252348 XM_005252349 XM_005252351 XM_005252354 XM_005252358 XM_006717365 XM_006717367 XM_006717368 XM_006717369 XM_006717370 XM_006717371 XM_006717372 XM_006717373 XM_006717374 XM_006717375
HUGO HGNC:2550
OMIM 602538
CCDS CCDS44354 CCDS41488 CCDS44355 CCDS44356
HPRD 03964
IMGT
EMBL AC026887 AF036956 AF090693 AF090694 AF295063 AF295064 AF295065 AF295066 AF295067 AF295068 AF314199 AF432906 AK299992 AK302681 AK316354 AL136320 AL157704 BC036391 CH471072 U69546
GenPept AAB09040 AAD02074 AAD13760 AAD13761 AAH36391 AAK72223 AAK72224 AAK92699 AAL27627 BAG61812 BAG63913 BAH14725 CAH70230 CAI20169 EAW86346
RNA Seq Atlas 10659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca