Version 5.4
Homo sapiens Gene: PDIA5
Summary
InnateDB Gene IDBG-52866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDIA5
Gene Name protein disulfide isomerase family A, member 5
Synonyms PDIR
Species Homo sapiens
Ensembl Gene ENSG00000065485
Encoded Proteins
IDBP-52868
protein disulfide isomerase family A, member 5
IDBP-485207
protein disulfide isomerase family A, member 5
IDBP-475698
protein disulfide isomerase family A, member 5
IDBP-480135
protein disulfide isomerase family A, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:123067062-123225227
Strand Forward strand
Band q21.1
Transcripts
ENST00000316218 ENSP00000323313
ENST00000489923 ENSP00000417520
ENST00000484644 ENSP00000419946
ENST00000495004
ENST00000472319
ENST00000467157
ENST00000485208
ENST00000469649 ENSP00000417199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
Biological Process
GO:0006457 protein folding
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0008152 metabolic process
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0034976 response to endoplasmic reticulum stress
GO:0044267 cellular protein metabolic process
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022844
View Gene Order
ENSBTAG00000018877
Not yet available
Pathways
NETPATH
REACTOME
REACT_18273
XBP1(S) activates chaperone genes pathway
REACT_18368
IRE1alpha activates chaperones pathway
REACT_18356
Unfolded Protein Response (UPR) pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 10954
UniGene Hs.477352
RefSeq NM_006810
HUGO HGNC:24811
OMIM
CCDS CCDS3020
HPRD 08334
IMGT
EMBL
GenPept
RNA Seq Atlas 102465667 10954

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca