Homo sapiens Gene: MPP3 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-52989.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | MPP3 | ||||||||||||||||||||||
Gene Name | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | ||||||||||||||||||||||
Synonyms | DLG3 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000161647 | ||||||||||||||||||||||
Encoded Proteins |
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008] This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn\'t encode a protein. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 17:43800799-43833170 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | q21.31 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | Q13368 | ||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 4356 | ||||||||||||||||||||||
UniGene | Hs.396566 | ||||||||||||||||||||||
RefSeq | NM_001932 XM_006721915 XM_006721917 | ||||||||||||||||||||||
HUGO | HGNC:7221 | ||||||||||||||||||||||
OMIM | 601114 | ||||||||||||||||||||||
CCDS | CCDS42344 | ||||||||||||||||||||||
HPRD | 03069 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | AK313045 AM050144 AM050145 BC047017 BC056865 CH471178 U37707 | ||||||||||||||||||||||
GenPept | AAB36964 AAH47017 AAH56865 BAG35877 CAJ18313 CAJ18315 EAW51664 EAW51665 | ||||||||||||||||||||||
RNA Seq Atlas | 4356 | ||||||||||||||||||||||