Version 5.4
Homo sapiens Gene: BCL2L2-PABPN1
Summary
InnateDB Gene IDBG-547352.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL2L2-PABPN1
Gene Name BCL2L2-PABPN1 readthrough
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000258643
Encoded Proteins
IDBP-596868
BCL2L2-PABPN1 readthrough
IDBP-592540
BCL2L2-PABPN1 readthrough
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring BCL2L2 (BCL2-like 2) and PABPN1 (poly(A) binding protein, nuclear 1) genes on chromosome 14. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:23306835-23325369
Strand Forward strand
Band q11.2
Transcripts
ENST00000553781 ENSP00000451320
ENST00000556100
ENST00000557008 ENSP00000452479
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007283 spermatogenesis
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005741 mitochondrial outer membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000092232
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q92843
TrEMBL G3V3B7 G3V3G8 G3V4T2 G3V5A9
UniProt Splice Variant
Entrez Gene 100529063
UniGene
RefSeq NM_001199864
HUGO HGNC:42959
OMIM 601931
CCDS CCDS55906
HPRD
IMGT
EMBL AK289519 AL049829 BC011637 BC021198 BC104789 BC113522 BT019549 CH471078 D87461 U59747
GenPept AAB09055 AAH21198 AAI04790 AAI13523 AAV38356 BAA19666 BAF82208 EAW66169
RNA Seq Atlas 100529063

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca