Version 5.4
Homo sapiens Gene: ELAVL2
Summary
InnateDB Gene IDBG-54761.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELAVL2
Gene Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
Synonyms HEL-N1; HELN1; HUB
Species Homo sapiens
Ensembl Gene ENSG00000107105
Encoded Proteins
IDBP-54763
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-54765
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-54767
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-235651
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-365376
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-365378
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
IDBP-595270
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3\' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:23690104-23826337
Strand Reverse strand
Band p21.3
Transcripts
ENST00000223951 ENSP00000223951
ENST00000380117 ENSP00000369460
ENST00000380110 ENSP00000369453
ENST00000397312 ENSP00000380479
ENST00000423281 ENSP00000391757
ENST00000440102 ENSP00000412602
ENST00000462649
ENST00000544538 ENSP00000440998
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008489
View Gene Order
ENSBTAG00000046348
Not yet available
Cross-References
SwissProt Q12926
TrEMBL B1AM48 C9JB16
UniProt Splice Variant
Entrez Gene 1993
UniGene Hs.166109
RefSeq NM_004432 XM_005251394 XM_006716736 XM_006716737 NM_001171195 NM_001171197 XM_005251390 XM_005251391 XM_005251392 XM_005251393 XM_005251395 XM_006716733 XM_006716734 XM_006716735 XM_006716738
HUGO HGNC:3313
OMIM 601673
CCDS CCDS6515 CCDS55298
HPRD 03396
IMGT
EMBL AB209294 AL161628 AL445623 BC030692 CH471071 U12431 U29943
GenPept AAA69698 AAA70417 AAH30692 BAD92531 CAC22160 CAI13376 EAW58581 EAW58582
RNA Seq Atlas 1993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca