Version 5.4
| Homo sapiens Gene: PSG9 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-55052.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | PSG9 | ||||||||||||||||||
| Gene Name | pregnancy specific beta-1-glycoprotein 9 | ||||||||||||||||||
| Synonyms | PS34; PSBG-11; PSBG-9; PSG11; PSGII | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000183668 | ||||||||||||||||||
| Encoded Proteins |
pregnancy specific beta-1-glycoprotein 9
pregnancy specific beta-1-glycoprotein 9
pregnancy specific beta-1-glycoprotein 9
pregnancy specific beta-1-glycoprotein 9
pregnancy specific beta-1-glycoprotein 9
pregnancy specific beta-1-glycoprotein 9
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009] The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 19:43211791-43269530 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q13.31 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | H7C1I4 Q9UMH8 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 5678 | ||||||||||||||||||
| UniGene | Hs.502092 Hs.679674 | ||||||||||||||||||
| RefSeq | NM_002784 XM_005259074 XM_005259075 XM_005259077 XM_005259078 XM_005259079 | ||||||||||||||||||
| HUGO | HGNC:9526 | ||||||||||||||||||
| OMIM | 176398 | ||||||||||||||||||
| CCDS | CCDS12618 | ||||||||||||||||||
| HPRD | 08897 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC005392 U08197 | ||||||||||||||||||
| GenPept | AAA18432 | ||||||||||||||||||
| RNA Seq Atlas | 5678 | ||||||||||||||||||