Version 5.4
Homo sapiens Gene: NAGK
Summary
InnateDB Gene IDBG-55848.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAGK
Gene Name N-acetylglucosamine kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124357
Encoded Proteins
IDBP-55850
N-acetylglucosamine kinase
IDBP-378927
N-acetylglucosamine kinase
IDBP-378928
N-acetylglucosamine kinase
IDBP-378932
N-acetylglucosamine kinase
IDBP-378933
N-acetylglucosamine kinase
IDBP-378937
N-acetylglucosamine kinase
IDBP-378945
N-acetylglucosamine kinase
IDBP-600603
N-acetylglucosamine kinase
IDBP-583764
N-acetylglucosamine kinase
IDBP-591434
N-acetylglucosamine kinase
IDBP-593334
N-acetylglucosamine kinase
IDBP-588759
N-acetylglucosamine kinase
IDBP-808022
N-acetylglucosamine kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:71064344-71079805
Strand Forward strand
Band p13.3
Transcripts
ENST00000244204 ENSP00000244204
ENST00000455197 ENSP00000408550
ENST00000418807 ENSP00000396070
ENST00000428360
ENST00000455662 ENSP00000389087
ENST00000443938 ENSP00000411846
ENST00000450272 ENSP00000400941
ENST00000443872 ENSP00000404531
ENST00000497690
ENST00000484984
ENST00000493102
ENST00000475709
ENST00000465105
ENST00000480411
ENST00000472519
ENST00000489309
ENST00000464638
ENST00000479854
ENST00000478659
ENST00000490998
ENST00000468601
ENST00000498022
ENST00000531799
ENST00000531934 ENSP00000436326
ENST00000533981 ENSP00000435207
ENST00000524736 ENSP00000435437
ENST00000529236 ENSP00000431204
ENST00000524537 ENSP00000437192
ENST00000613852 ENSP00000477639
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 57 [view]
Protein-Protein 54 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0009384 N-acylmannosamine kinase activity
GO:0045127 N-acetylglucosamine kinase activity
Biological Process
GO:0006044 N-acetylglucosamine metabolic process
GO:0006051 N-acetylmannosamine metabolic process
GO:0019262 N-acetylneuraminate catabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034744
View Gene Order
ENSBTAG00000014668
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
INOH website
Aminosugars metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.7036
RefSeq NM_017567 XM_005264412 XM_006712045
HUGO
OMIM
CCDS CCDS33220
HPRD 08441
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca