Version 5.4
Homo sapiens Gene: PCGF1
Summary
InnateDB Gene IDBG-57564.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCGF1
Gene Name polycomb group ring finger 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115289
Encoded Proteins
IDBP-57566
polycomb group ring finger 1
IDBP-812087
polycomb group ring finger 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:74505043-74508580
Strand Reverse strand
Band p13.1
Transcripts
ENST00000233630 ENSP00000233630
ENST00000465993
ENST00000475863
ENST00000489914
ENST00000480844
ENST00000463744
ENST00000496911
ENST00000612049 ENSP00000478746
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0035518 histone H2A monoubiquitination
Cellular Component
GO:0005634 nucleus
GO:0031519 PcG protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000069678
View Gene Order
ENSBTAG00000016606
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_032673 XM_005264616 XM_005264618
HUGO
OMIM
CCDS CCDS1946
HPRD 11404
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca