Version 5.4
| Homo sapiens Gene: MRPL19 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-58203.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | MRPL19 | ||||||||||||||||||
| Gene Name | mitochondrial ribosomal protein L19 | ||||||||||||||||||
| Synonyms | L19mt; MRP-L15; MRP-L19; MRPL15; RLX1; RPML15 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000115364 | ||||||||||||||||||
| Encoded Proteins |
mitochondrial ribosomal protein L19
mitochondrial ribosomal protein L19
mitochondrial ribosomal protein L19
mitochondrial ribosomal protein L19
mitochondrial ribosomal protein L19
mitochondrial ribosomal protein L19
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75%% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 2:75646783-75690851 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p12 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
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| KEGG |
Ribosome pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | H7C2J0 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 9801 | ||||||||||||||||||
| UniGene | Hs.44024 Hs.592966 Hs.738878 | ||||||||||||||||||
| RefSeq | NM_014763 XM_006712155 | ||||||||||||||||||
| HUGO | HGNC:14052 | ||||||||||||||||||
| OMIM | 611832 | ||||||||||||||||||
| CCDS | CCDS1960 | ||||||||||||||||||
| HPRD | 11370 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC005034 | ||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | 9801 | ||||||||||||||||||