Version 5.4
Homo sapiens Gene: THOC3
Summary
InnateDB Gene IDBG-58545.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THOC3
Gene Name THO complex 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000051596
Encoded Proteins
IDBP-58547
THO complex 3
IDBP-375144
THO complex 3
IDBP-475366
THO complex 3
IDBP-475387
THO complex 3
IDBP-481403
THO complex 3
IDBP-479034
THO complex 3
IDBP-481216
THO complex 3
IDBP-474893
THO complex 3
IDBP-484547
THO complex 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:175917873-176034680
Strand Reverse strand
Band q35.2
Transcripts
ENST00000265097 ENSP00000265097
ENST00000432305 ENSP00000394166
ENST00000515016 ENSP00000425781
ENST00000505969 ENSP00000424967
ENST00000514861 ENSP00000425039
ENST00000513482 ENSP00000422243
ENST00000510300
ENST00000511062 ENSP00000427029
ENST00000513118
ENST00000513006 ENSP00000421082
ENST00000514250 ENSP00000427267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 28 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0046784 intronless viral mRNA export from host nucleus
Cellular Component
GO:0000346 transcription export complex
GO:0000445 THO complex part of transcription export complex
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025872
View Gene Order
ENSBTAG00000035174
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.484227 Hs.535769 Hs.623598 Hs.635768
RefSeq NM_032361
HUGO
OMIM
CCDS CCDS4397
HPRD 09497
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca