Version 5.4
Homo sapiens Gene: CDYL
Summary
InnateDB Gene IDBG-58613.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDYL
Gene Name chromodomain protein, Y-like
Synonyms CDYL1
Species Homo sapiens
Ensembl Gene ENSG00000153046
Encoded Proteins
IDBP-58615
chromodomain protein, Y-like
IDBP-58617
chromodomain protein, Y-like
IDBP-235033
chromodomain protein, Y-like
IDBP-361134
chromodomain protein, Y-like
IDBP-361141
chromodomain protein, Y-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:4706159-4955551
Strand Forward strand
Band p25.1
Transcripts
ENST00000328908 ENSP00000330512
ENST00000343762 ENSP00000340908
ENST00000397588 ENSP00000380718
ENST00000440139 ENSP00000394740
ENST00000449732 ENSP00000394076
ENST00000491864
ENST00000483019
ENST00000472453
ENST00000469671
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0003824 catalytic activity
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007283 spermatogenesis
GO:0008152 metabolic process
GO:0016573 histone acetylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059288
View Gene Order
ENSBTAG00000016397
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.269092 Hs.705841
RefSeq NM_001143970 NM_001143971 NM_004824 XM_006715272
HUGO
OMIM
CCDS CCDS4491 CCDS47364
HPRD 04803
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca