Version 5.4
| Homo sapiens Gene: SLC29A2 | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-58944.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | SLC29A2 | ||||||||||||||||||
| Gene Name | solute carrier family 29 (nucleoside transporters), member 2 | ||||||||||||||||||
| Synonyms | DER12; ENT2; HNP36 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000174669 | ||||||||||||||||||
| Encoded Proteins |
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (nucleoside transporters), member 2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
|
||||||||||||||||||
| Protein Structure |
|
||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008] |
||||||||||||||||||
| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:66362521-66372214 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q13.2 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
| Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
| Biological Process |
|
||||||||||||||||||
| Cellular Component |
|
||||||||||||||||||
| Orthologs | |||||||||||||||||||
|
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
Transport of vitamins, nucleosides, and related molecules pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
|
||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q14542 | ||||||||||||||||||
| TrEMBL | G5E943 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 3177 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001300868 NM_001300869 NM_001532 XM_006718525 XM_006718527 XM_006718528 | ||||||||||||||||||
| HUGO | HGNC:11004 | ||||||||||||||||||
| OMIM | 602110 | ||||||||||||||||||
| CCDS | CCDS73326 CCDS8137 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF029358 AF034102 AF401235 AK057041 AP001107 BC093634 CH471076 X86681 | ||||||||||||||||||
| GenPept | AAB97834 AAC39526 AAH93634 AAK92533 BAG51849 CAA60380 EAW74519 EAW74521 EAW74522 | ||||||||||||||||||
| RNA Seq Atlas | 3177 | ||||||||||||||||||