Version 5.4
Homo sapiens Gene: WSB2
Summary
InnateDB Gene IDBG-59659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WSB2
Gene Name WD repeat and SOCS box containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176871
Encoded Proteins
IDBP-59661
WD repeat and SOCS box containing 2
IDBP-383915
WD repeat and SOCS box containing 2
IDBP-597369
WD repeat and SOCS box containing 2
IDBP-601765
WD repeat and SOCS box containing 2
IDBP-592197
WD repeat and SOCS box containing 2
IDBP-592382
WD repeat and SOCS box containing 2
IDBP-598405
WD repeat and SOCS box containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:118032694-118062430
Strand Reverse strand
Band q24.23
Transcripts
ENST00000315436 ENSP00000319474
ENST00000441406 ENSP00000409131
ENST00000543218 ENSP00000438433
ENST00000535496 ENSP00000439450
ENST00000540129
ENST00000543186 ENSP00000445547
ENST00000536738
ENST00000537945 ENSP00000440386
ENST00000536602
ENST00000542726
ENST00000544233 ENSP00000444431
ENST00000614776
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029364
View Gene Order
ENSBTAG00000007139
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.506985
RefSeq NM_001278557 NM_001278558 NM_018639
HUGO
OMIM
CCDS CCDS61251 CCDS61252 CCDS9186
HPRD 18305
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca