InnateDB Gene
|
IDBG-60077.5
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
CST9
|
Gene Name
|
cystatin 9 (testatin)
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Gene
|
ENSG00000173335
|
Encoded Proteins
|
|
Protein Structure
|
|
Useful resources
|
Stemformatics
EHFPI
ImmGen
|
Summary |
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted protein that may play a role in hematopoietic differentiation or inflammation. [provided by RefSeq, Jul 2008]
|
Type |
Protein coding
|
Genomic Location
|
Chromosome 20:23602410-23605876
|
Strand
|
Reverse strand
|
Band
|
p11.21
|
Transcripts
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
0
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0004869
|
cysteine-type endopeptidase inhibitor activity
|
|
Biological Process |
GO:0010951
|
negative regulation of endopeptidase activity
|
|
Cellular Component |
|
|
No orthologs found for this gene |
SwissProt
|
Q5W186
|
TrEMBL
|
|
UniProt Splice Variant
|
|
Entrez Gene
|
128822
|
UniGene
|
Hs.698020
|
RefSeq
|
NM_001008693
|
HUGO
|
HGNC:13261
|
OMIM
|
|
CCDS
|
CCDS33450
|
HPRD |
|
IMGT
|
|
EMBL
|
AF494536
AL121894
BC137302
BC137303
|
GenPept
|
AAI37303
AAI37304
AAM18055
CAH71437
|
RNA Seq Atlas
|
128822
|
|
|