Version 5.4
Homo sapiens Gene: ALDH3B2
Summary
InnateDB Gene IDBG-60949.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH3B2
Gene Name aldehyde dehydrogenase 3 family, member B2
Synonyms ALDH8
Species Homo sapiens
Ensembl Gene ENSG00000132746
Encoded Proteins
IDBP-60951
aldehyde dehydrogenase 3 family, member B2
IDBP-591139
aldehyde dehydrogenase 3 family, member B2
IDBP-590393
aldehyde dehydrogenase 3 family, member B2
IDBP-599902
aldehyde dehydrogenase 3 family, member B2
IDBP-593624
aldehyde dehydrogenase 3 family, member B2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:67662162-67681200
Strand Reverse strand
Band q13.2
Transcripts
ENST00000349015 ENSP00000255084
ENST00000530069 ENSP00000431595
ENST00000531248 ENSP00000435476
ENST00000534425
ENST00000525827 ENSP00000433718
ENST00000528756 ENSP00000433466
ENST00000531881
ENST00000533962
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004028 3-chloroallyl aldehyde dehydrogenase activity
GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006066 alcohol metabolic process
GO:0006068 ethanol catabolic process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000075296
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00340
Histidine metabolism pathway
hsa00360
Phenylalanine metabolism pathway
hsa00350
Tyrosine metabolism pathway
hsa00410
beta-Alanine metabolism pathway
hsa00980
Metabolism of xenobiotics by cytochrome P450 pathway
hsa00982
Drug metabolism pathway
INOH
INOH website
Phenylalanine degradation pathway
INOH website
Tyrosine metabolism pathway
INOH website
Histidine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.87539
RefSeq NM_000695 NM_001031615
HUGO
OMIM
CCDS CCDS31622
HPRD 03559
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca