Version 5.4
Homo sapiens Gene: SUN1
Summary
InnateDB Gene IDBG-6219.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUN1
Gene Name Sad1 and UNC84 domain containing 1
Synonyms UNC84A
Species Homo sapiens
Ensembl Gene ENSG00000164828
Encoded Proteins
IDBP-6227
Sad1 and UNC84 domain containing 1
IDBP-292454
Sad1 and UNC84 domain containing 1
IDBP-292455
Sad1 and UNC84 domain containing 1
IDBP-292458
Sad1 and UNC84 domain containing 1
IDBP-360976
Sad1 and UNC84 domain containing 1
IDBP-360980
Sad1 and UNC84 domain containing 1
IDBP-360986
Sad1 and UNC84 domain containing 1
IDBP-360992
Sad1 and UNC84 domain containing 1
IDBP-360996
Sad1 and UNC84 domain containing 1
IDBP-360997
Sad1 and UNC84 domain containing 1
IDBP-361001
Sad1 and UNC84 domain containing 1
IDBP-361003
Sad1 and UNC84 domain containing 1
IDBP-361004
Sad1 and UNC84 domain containing 1
IDBP-361008
Sad1 and UNC84 domain containing 1
IDBP-361009
Sad1 and UNC84 domain containing 1
IDBP-361012
Sad1 and UNC84 domain containing 1
IDBP-361014
Sad1 and UNC84 domain containing 1
IDBP-361016
Sad1 and UNC84 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:816615-896435
Strand Forward strand
Band p22.3
Transcripts
ENST00000340926
ENST00000389574 ENSP00000374225
ENST00000405266 ENSP00000384116
ENST00000401592 ENSP00000384015
ENST00000403868 ENSP00000383947
ENST00000425407 ENSP00000392309
ENST00000452783 ENSP00000413439
ENST00000413171
ENST00000457378 ENSP00000395952
ENST00000450538
ENST00000427969
ENST00000435699 ENSP00000388430
ENST00000440380 ENSP00000399549
ENST00000439679 ENSP00000413188
ENST00000424128 ENSP00000394597
ENST00000457598 ENSP00000404965
ENST00000421580 ENSP00000394381
ENST00000450881 ENSP00000392595
ENST00000419312 ENSP00000414279
ENST00000429178 ENSP00000409909
ENST00000433212 ENSP00000406653
ENST00000457861 ENSP00000406444
ENST00000467483
ENST00000483996
ENST00000469755
ENST00000493681
ENST00000477950
ENST00000471349
ENST00000464442
ENST00000480475
ENST00000488628
ENST00000463848
ENST00000459810
ENST00000475971
ENST00000497943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005521 lamin binding
Biological Process
GO:0006998 nuclear envelope organization
GO:0090286 cytoskeletal anchoring at nuclear membrane
GO:0090292 nuclear matrix anchoring at nuclear membrane
Cellular Component
GO:0002080 acrosomal membrane
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005639 integral component of nuclear inner membrane
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0034993 SUN-KASH complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000036817
View Gene Order
Pathways
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.438072 Hs.602725 Hs.708379
RefSeq NM_001130965 NM_001171944 NM_001171945 NM_001171946 NM_025154
HUGO
OMIM
CCDS CCDS43533 CCDS47525 CCDS55078 CCDS55079 CCDS55080
HPRD 16257
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca