Version 5.4
Homo sapiens Gene: ALDH16A1
Summary
InnateDB Gene IDBG-62756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH16A1
Gene Name aldehyde dehydrogenase 16 family, member A1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000161618
Encoded Proteins
IDBP-62758
aldehyde dehydrogenase 16 family, member A1
IDBP-383234
aldehyde dehydrogenase 16 family, member A1
IDBP-598947
aldehyde dehydrogenase 16 family, member A1
IDBP-763336
IDBP-762549
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49453169-49471048
Strand Forward strand
Band q13.33
Transcripts
ENST00000293350 ENSP00000293350
ENST00000455361 ENSP00000410142
ENST00000540132 ENSP00000445088
ENST00000593417 ENSP00000470160
ENST00000594549
ENST00000599652
ENST00000600265 ENSP00000469507
ENST00000598015
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000007833
View Gene Order
ENSBTAG00000000330
Not yet available
Cross-References
SwissProt
TrEMBL M0QYY1
UniProt Splice Variant
Entrez Gene 126133
UniGene Hs.618753 Hs.719998
RefSeq NM_001145396 NM_153329
HUGO HGNC:28114
OMIM 613358
CCDS CCDS12766 CCDS46141
HPRD 14394
IMGT
EMBL AC010619
GenPept
RNA Seq Atlas 126133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca