Version 5.4
| Bos taurus Gene: FBXW11 | |||||||||||||||||||||
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| Summary | |||||||||||||||||||||
| InnateDB Gene | IDBG-628478.3 | ||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
| Gene Symbol | FBXW11 | ||||||||||||||||||||
| Gene Name | Uncharacterized protein | ||||||||||||||||||||
| Synonyms | |||||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||||
| Ensembl Gene | ENSBTAG00000015376 | ||||||||||||||||||||
| Encoded Proteins |
F-box and WD repeat domain containing 11
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| Protein Structure | |||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072803:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||
| Genomic Location | Chromosome 20:3584765-3624526 | ||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||
| Band | |||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
| NETPATH |
TNFalpha pathway
Prolactin pathway
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| REACTOME |
Regulation of PLK1 Activity at G2/M Transition pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Activation of NF-kappaB in B cells pathway
Cell Cycle pathway
Adaptive Immune System pathway
Immune System pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Class I MHC mediated antigen processing & presentation pathway
Mitotic G2-G2/M phases pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
G2/M Transition pathway
Signaling by the B Cell Receptor (BCR) pathway
Cell Cycle, Mitotic pathway
Class I MHC mediated antigen processing & presentation pathway
Cell Cycle pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Mitotic G2-G2/M phases pathway
Activation of NF-kappaB in B cells pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Adaptive Immune System pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
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| KEGG |
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Ubiquitin mediated proteolysis pathway
Circadian rhythm pathway
Oocyte meiosis pathway
Shigellosis pathway
Ubiquitin mediated proteolysis pathway
Wnt signaling pathway pathway
Hedgehog signaling pathway pathway
Circadian rhythm pathway
Oocyte meiosis pathway
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| INOH | |||||||||||||||||||||
| PID NCI |
Presenilin action in Notch and Wnt signaling
Signaling events mediated by VEGFR1 and VEGFR2
Hedgehog signaling events mediated by Gli proteins
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| Cross-References | |||||||||||||||||||||
| SwissProt | |||||||||||||||||||||
| TrEMBL | F1MLG0 | ||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||
| Entrez Gene | 540642 | ||||||||||||||||||||
| UniGene | |||||||||||||||||||||
| RefSeq | XM_002696250 XM_003583666 XM_003583667 XM_003583668 XM_003587498 XM_003587499 XM_003587500 XM_005196113 XM_005196114 XM_005196115 XM_005221422 XM_005221423 XM_005221424 XM_612428 | ||||||||||||||||||||
| HUGO | HGNC:13607 | ||||||||||||||||||||
| OMIM | |||||||||||||||||||||
| CCDS | |||||||||||||||||||||
| HPRD | |||||||||||||||||||||
| IMGT | |||||||||||||||||||||
| EMBL | DAAA02049882 DAAA02049883 | ||||||||||||||||||||
| GenPept | |||||||||||||||||||||
| RNA Seq Atlas | 540642 | ||||||||||||||||||||