InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SOD1

Summary

InnateDB Gene

IDBG-630058.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SOD1

Gene Name

Superoxide dismutase

Synonyms

SOD1L1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018854

Encoded Proteins

IDBP-681496

Superoxide dismutase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:3113949-3122613

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000032452

ENSBTAP00000032384

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004784	superoxide dismutase activity
GO:0004842	ubiquitin-protein transferase activity
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016209	antioxidant activity
GO:0016491	oxidoreductase activity
GO:0030346	protein phosphatase 2B binding
GO:0046872	metal ion binding
GO:0051087	chaperone binding

Biological Process

GO:0000187	activation of MAPK activity
GO:0000209	protein polyubiquitination
GO:0000303	response to superoxide
GO:0001541	ovarian follicle development
GO:0001817	regulation of cytokine production
GO:0001819	positive regulation of cytokine production
GO:0001895	retina homeostasis
GO:0002262	myeloid cell homeostasis
GO:0006302	double-strand break repair
GO:0006309	apoptotic DNA fragmentation
GO:0006749	glutathione metabolic process
GO:0006801	superoxide metabolic process
GO:0006879	cellular iron ion homeostasis
GO:0007283	spermatogenesis
GO:0007566	embryo implantation
GO:0007569	cell aging
GO:0007605	sensory perception of sound
GO:0007626	locomotory behavior
GO:0008217	regulation of blood pressure
GO:0009408	response to heat
GO:0010033	response to organic substance
GO:0019226	transmission of nerve impulse
GO:0019430	removal of superoxide radicals
GO:0032287	peripheral nervous system myelin maintenance
GO:0040014	regulation of multicellular organism growth
GO:0042493	response to drug
GO:0042542	response to hydrogen peroxide
GO:0043085	positive regulation of catalytic activity
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0044419	interspecies interaction between organisms
GO:0045471	response to ethanol
GO:0045541	negative regulation of cholesterol biosynthetic process
GO:0045859	regulation of protein kinase activity
GO:0046716	muscle cell cellular homeostasis
GO:0048678	response to axon injury
GO:0050665	hydrogen peroxide biosynthetic process
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0051881	regulation of mitochondrial membrane potential
GO:0055114	oxidation-reduction process
GO:0060047	heart contraction
GO:0060052	neurofilament cytoskeleton organization
GO:0060087	relaxation of vascular smooth muscle
GO:0060088	auditory receptor cell stereocilium organization
GO:0072593	reactive oxygen species metabolic process

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0031012	extracellular matrix
GO:0031410	cytoplasmic vesicle
GO:0032839	dendrite cytoplasm
GO:0043025	neuronal cell body
GO:0043234	protein complex