Version 5.4
Homo sapiens Gene: RRAS
Summary
InnateDB Gene IDBG-63131.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RRAS
Gene Name related RAS viral (r-ras) oncogene homolog
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126458
Encoded Proteins
IDBP-63133
related RAS viral (r-ras) oncogene homolog
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49635292-49640201
Strand Reverse strand
Band q13.33
Transcripts
ENST00000246792 ENSP00000246792
ENST00000601532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 19 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
GO:0032403 protein complex binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0007268 synaptic transmission
GO:0007411 axon guidance
GO:0015031 protein transport
GO:0030336 negative regulation of cell migration
GO:0045766 positive regulation of angiogenesis
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038387
View Gene Order
ENSBTAG00000020983
Not yet available
Pathways
NETPATH
REACTOME
REACT_20568
CREB phosphorylation through the activation of Ras pathway
REACT_19266
Sema4D mediated inhibition of cell attachment and migration pathway
REACT_19259
Sema4D in semaphorin signaling pathway
REACT_19279
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_13685
Neuronal System pathway
REACT_18266
Axon guidance pathway
REACT_20593
Post NMDA receptor activation events pathway
REACT_20563
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04010
MAPK signaling pathway pathway
hsa04530
Tight junction pathway
INOH
PID NCI
plexind1_pathway
Plexin-D1 Signaling
fak_pathway
Signaling events mediated by focal adhesion kinase
ephbfwdpathway
EPHB forward signaling
ras_pathway
Regulation of Ras family activation
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_006270
HUGO
OMIM
CCDS CCDS12774
HPRD 01299
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca