Version 5.4
Homo sapiens Gene: PDCL3
Summary
InnateDB Gene IDBG-63625.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCL3
Gene Name phosducin-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115539
Encoded Proteins
IDBP-63627
phosducin-like 3
IDBP-383652
phosducin-like 3
IDBP-383653
phosducin-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:100562690-100576735
Strand Forward strand
Band q11.2
Transcripts
ENST00000264254 ENSP00000264254
ENST00000416255 ENSP00000413936
ENST00000450127 ENSP00000390585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0044183 protein binding involved in protein folding
Biological Process
GO:0001525 angiogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0006457 protein folding
GO:0006915 apoptotic process
GO:0016032 viral process
GO:0045766 positive regulation of angiogenesis
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026078
View Gene Order
ENSBTAG00000009962
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 79031
UniGene Hs.661514
RefSeq NM_024065
HUGO HGNC:28860
OMIM 611678
CCDS CCDS33261
HPRD 17827
IMGT
EMBL
GenPept
RNA Seq Atlas 79031

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca