Version 5.4
Bos taurus Gene: CUGBP1
Summary
InnateDB Gene IDBG-637471.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CUGBP1
Gene Name CUGBP Elav-like family member 1
Synonyms CUGBP1
Species Bos taurus
Ensembl Gene ENSBTAG00000002520
Encoded Proteins
IDBP-689485
CUGBP Elav-like family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149187:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:78490888-78570865
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003274 ENSBTAP00000003274
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
GO:0042835 BRE binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006376 mRNA splice site selection
GO:0007286 spermatid development
GO:0040018 positive regulation of multicellular organism growth
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000149187
View Gene Order
ENSMUSG00000005506
View Gene Order
Cross-References
SwissProt
TrEMBL A7MB95
UniProt Splice Variant
Entrez Gene 540475
UniGene Bt.16531
RefSeq NM_001101212
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151433 DAAA02041602 DAAA02041603 DAAA02041604
GenPept AAI51434
RNA Seq Atlas 540475

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca