InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BMI1

Summary

InnateDB Gene

IDBG-637604.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BMI1

Gene Name

Polycomb complex protein BMI-1

Synonyms

PCGF4

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015584

Encoded Proteins

IDBP-689632

Polycomb complex protein BMI-1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168283:
This locus represents naturally occurring read-through transcription between the neighboring COMM domain-containing protein 3 and polycomb complex protein BMI-1 genes on chromosome 10. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:23709778-23712913

Strand

Forward strand

Band

Transcripts

ENSBTAT00000020705

ENSBTAP00000020705

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.

Predicted by orthology
Total	81 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001501	skeletal system development
GO:0001701	in utero embryonic development
GO:0006306	DNA methylation
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006959	humoral immune response
GO:0007420	brain development
GO:0016568	chromatin modification
GO:0016573	histone acetylation
GO:0016574	histone ubiquitination
GO:0021903	rostrocaudal neural tube patterning
GO:0030890	positive regulation of B cell proliferation
GO:0033092	positive regulation of immature T cell proliferation in thymus
GO:0048103	somatic stem cell division
GO:0048704	embryonic skeletal system morphogenesis
GO:0048706	embryonic skeletal system development
GO:0051443	positive regulation of ubiquitin-protein transferase activity
GO:2001234	negative regulation of apoptotic signaling pathway