Version 5.4
Homo sapiens Gene: TPX2
Summary
InnateDB Gene IDBG-63816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPX2
Gene Name TPX2, microtubule-associated, homolog (Xenopus laevis)
Synonyms C20orf1; C20orf2; DIL-2; DIL2; FLS353; GD:C20orf1; HCA519; HCTP4; p100; REPP86
Species Homo sapiens
Ensembl Gene ENSG00000088325
Encoded Proteins
IDBP-63818
TPX2, microtubule-associated, homolog (Xenopus laevis)
IDBP-63820
TPX2, microtubule-associated, homolog (Xenopus laevis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 20:31739271-31801805
Strand Forward strand
Band q11.21
Transcripts
ENST00000340513 ENSP00000341145
ENST00000300403 ENSP00000300403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
Experimentally validated
Total 43 [view]
Protein-Protein 41 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0019901 protein kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0007067 mitotic nuclear division
GO:0008283 cell proliferation
GO:0032147 activation of protein kinase activity
GO:0060236 regulation of mitotic spindle organization
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0043203 axon hillock
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027469
View Gene Order
ENSBTAG00000018775
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
aurora_a_pathway
Aurora A signaling
plk1_pathway
PLK1 signaling events
Cross-References
SwissProt Q9ULW0
TrEMBL B3KM90 Q643R0 Q96FC3 Q96RR5
UniProt Splice Variant
Entrez Gene 22974
UniGene Hs.244580
RefSeq NM_012112 XM_005260340
HUGO HGNC:1249
OMIM 605917
CCDS CCDS13190
HPRD
IMGT
EMBL AB024704 AB027467 AF098158 AF146731 AF244547 AF287265 AK001391 AK312549 AL117534 AL160175 AY734680 BC004136 BC011357 BC020207 CH471077
GenPept AAD33965 AAF03248 AAF81695 AAH04136 AAH11357 AAH20207 AAK83033 AAU29203 BAA76931 BAA85893 BAG35446 BAG50902 CAB55982 CAD38007 EAW76418 EAW76419 EAW76421 EAW76422
RNA Seq Atlas 22974

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca