Version 5.4
Bos taurus Gene: MPP7
Summary
InnateDB Gene IDBG-638675.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPP7
Gene Name MAGUK p55 subfamily member 7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017354
Encoded Proteins
IDBP-690763
MAGUK p55 subfamily member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150054:
Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:36610252-36833259
Strand Forward strand
Band
Transcripts
ENSBTAT00000036314 ENSBTAP00000036176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0032947 protein complex scaffold
GO:0046982 protein heterodimerization activity
Biological Process
GO:0070830 tight junction assembly
GO:0071896 protein localization to adherens junction
Cellular Component
GO:0005739 mitochondrion
GO:0005912 adherens junction
GO:0005923 tight junction
GO:0016020 membrane
GO:0030054 cell junction
GO:0097025 MPP7-DLG1-LIN7 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000150054
View Gene Order
ENSMUSG00000057440
View Gene Order
Cross-References
SwissProt A6QQZ7
TrEMBL
UniProt Splice Variant
Entrez Gene 512659
UniGene Bt.47758
RefSeq NM_001100347
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC150055
GenPept AAI50056
RNA Seq Atlas 512659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca