Version 5.4
Homo sapiens Gene: ATF5
Summary
InnateDB Gene IDBG-63891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATF5
Gene Name activating transcription factor 5
Synonyms ATFX; HMFN0395
Species Homo sapiens
Ensembl Gene ENSG00000169136
Encoded Proteins
IDBP-383613
activating transcription factor 5
IDBP-764698
IDBP-765901
IDBP-762064
IDBP-764386
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:49928702-49933935
Strand Forward strand
Band q13.33
Transcripts
ENST00000423777 ENSP00000396954
ENST00000600336 ENSP00000471162
ENST00000597227 ENSP00000470978
ENST00000596658 ENSP00000470464
ENST00000595125 ENSP00000470633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0031072 heat shock protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0009791 post-embryonic development
GO:0010468 regulation of gene expression
GO:0021889 olfactory bulb interneuron differentiation
GO:0021891 olfactory bulb interneuron development
GO:0021988 olfactory lobe development
GO:0035264 multicellular organism growth
GO:0043066 negative regulation of apoptotic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048712 negative regulation of astrocyte differentiation
GO:0050768 negative regulation of neurogenesis
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038539
View Gene Order
ENSBTAG00000003457
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
prlsignalingeventspathway
Signaling events mediated by PRL
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.9754
RefSeq NM_001193646 NM_012068
HUGO
OMIM
CCDS CCDS12789
HPRD 05906
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca