Version 5.4
Bos taurus Gene: TFR2
Summary
InnateDB Gene IDBG-640543.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFR2
Gene Name transferrin receptor protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011738
Encoded Proteins
IDBP-692816
transferrin receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106327:
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:36471291-36482523
Strand Forward strand
Band
Transcripts
ENSBTAT00000015588 ENSBTAP00000015588
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000106327
View Gene Order
ENSMUSG00000029716
View Gene Order
Cross-References
SwissProt
TrEMBL F1MF47
UniProt Splice Variant
Entrez Gene 617916
UniGene Bt.6186
RefSeq NM_001177741
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058278
GenPept
RNA Seq Atlas 617916

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca