Version 5.4
Homo sapiens Gene: FOXS1
Summary
InnateDB Gene IDBG-64091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXS1
Gene Name forkhead box S1
Synonyms FKHL18; FREAC10
Species Homo sapiens
Ensembl Gene ENSG00000179772
Encoded Proteins
IDBP-64093
forkhead box S1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and kidney. The function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:31844301-31845619
Strand Reverse strand
Band q11.21
Transcripts
ENST00000375978 ENSP00000365145
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001568 blood vessel development
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0040018 positive regulation of multicellular organism growth
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050885 neuromuscular process controlling balance
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000074676
View Gene Order
ENSBTAG00000009206
Not yet available
Cross-References
SwissProt O43638
TrEMBL
UniProt Splice Variant
Entrez Gene 2307
UniGene Hs.516971
RefSeq NM_004118
HUGO HGNC:3735
OMIM 602939
CCDS CCDS13192
HPRD
IMGT
EMBL AF042831 AL160175 BC013408 BT009768
GenPept AAC15420 AAH13408 AAP88770 CAI12817
RNA Seq Atlas 2307

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca