Bos taurus Gene: PLA2G6 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-641594.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | PLA2G6 | ||||||
Gene Name | Uncharacterized protein | ||||||
Synonyms | |||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000014015 | ||||||
Encoded Proteins |
phospholipase A2, group VI (cytosolic, calcium-independent)
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184381:
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 5:110404232-110450529 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Role of phospholipids in phagocytosis pathway
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PE pathway
Acyl chain remodeling of CL pathway
Metabolism of lipids and lipoproteins pathway
Innate Immune System pathway
Glycerophospholipid biosynthesis pathway
Immune System pathway
Phospholipid metabolism pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Metabolism pathway
Innate Immune System pathway
Acyl chain remodelling of PC pathway
Acyl chain remodeling of CL pathway
Role of phospholipids in phagocytosis pathway
Acyl chain remodelling of PE pathway
Metabolism pathway
Immune System pathway
Metabolism of lipids and lipoproteins pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
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KEGG |
alpha-Linolenic acid metabolism pathway
Arachidonic acid metabolism pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Ether lipid metabolism pathway
Fc gamma R-mediated phagocytosis pathway
Vascular smooth muscle contraction pathway
Glycerophospholipid metabolism pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Linoleic acid metabolism pathway
alpha-Linolenic acid metabolism pathway
Fc gamma R-mediated phagocytosis pathway
Vascular smooth muscle contraction pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | E1BB89 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 535381 | ||||||
UniGene | Bt.109508 | ||||||
RefSeq | XM_001251754 XM_002687923 XM_005198502 XM_005207366 | ||||||
HUGO | HGNC:9039 | ||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | DAAA02014653 | ||||||
GenPept | |||||||
RNA Seq Atlas | 535381 | ||||||