Bos taurus Gene: TGM2 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-642580.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | TGM2 | ||||||||||||||||
Gene Name | Protein-glutamine gamma-glutamyltransferase 2 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000016208 | ||||||||||||||||
Encoded Proteins |
protein-glutamine gamma-glutamyltransferase 2
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198959:
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 13:67663138-67697607 | ||||||||||||||||
Strand | Reverse strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH |
FSH pathway
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REACTOME | |||||||||||||||||
KEGG |
Huntington's disease pathway
Huntington's disease pathway
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INOH | |||||||||||||||||
PID NCI |
Thromboxane A2 receptor signaling
Beta1 integrin cell surface interactions
Alpha9 beta1 integrin signaling events
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Cross-References | |||||||||||||||||
SwissProt | P51176 | ||||||||||||||||
TrEMBL | |||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 281528 | ||||||||||||||||
UniGene | Bt.5401 | ||||||||||||||||
RefSeq | NM_177507 | ||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | BC103290 X60686 | ||||||||||||||||
GenPept | AAI03291 CAA43097 | ||||||||||||||||
RNA Seq Atlas | 281528 | ||||||||||||||||