Homo sapiens Gene: KCNE3 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-64310.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | KCNE3 | ||||||||||||||||||
Gene Name | potassium voltage-gated channel, Isk-related family, member 3 | ||||||||||||||||||
Synonyms | HOKPP; HYPP; MiRP2 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000175538 | ||||||||||||||||||
Encoded Proteins |
potassium voltage-gated channel, Isk-related family, member 3
potassium voltage-gated channel, Isk-related family, member 3
potassium voltage-gated channel, Isk-related family, member 3
potassium voltage-gated channel, Isk-related family, member 3
potassium voltage-gated channel, Isk-related family, member 3
potassium voltage-gated channel, Isk-related family, member 3
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 11:74454841-74467729 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | q13.4 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME | |||||||||||||||||||
KEGG |
Protein digestion and absorption pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | E9PJV9 E9PN03 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 10008 | ||||||||||||||||||
UniGene | Hs.523899 | ||||||||||||||||||
RefSeq | NM_005472 | ||||||||||||||||||
HUGO | HGNC:6243 | ||||||||||||||||||
OMIM | 604433 | ||||||||||||||||||
CCDS | CCDS8232 | ||||||||||||||||||
HPRD | 07256 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AP001372 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 10008 | ||||||||||||||||||