Version 5.4
Homo sapiens Gene: PHC3
Summary
InnateDB Gene IDBG-64379.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHC3
Gene Name polyhomeotic homolog 3 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173889
Encoded Proteins
IDBP-483529
polyhomeotic homolog 3 (Drosophila)
IDBP-476806
polyhomeotic homolog 3 (Drosophila)
IDBP-476052
polyhomeotic homolog 3 (Drosophila)
IDBP-473686
polyhomeotic homolog 3 (Drosophila)
IDBP-478155
polyhomeotic homolog 3 (Drosophila)
IDBP-479888
polyhomeotic homolog 3 (Drosophila)
IDBP-481876
polyhomeotic homolog 3 (Drosophila)
IDBP-473875
polyhomeotic homolog 3 (Drosophila)
IDBP-480153
polyhomeotic homolog 3 (Drosophila)
IDBP-475652
polyhomeotic homolog 3 (Drosophila)
IDBP-474069
polyhomeotic homolog 3 (Drosophila)
IDBP-475122
polyhomeotic homolog 3 (Drosophila)
IDBP-474404
polyhomeotic homolog 3 (Drosophila)
IDBP-479453
polyhomeotic homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:170086732-170181749
Strand Reverse strand
Band q26.2
Transcripts
ENST00000484068 ENSP00000418835
ENST00000494943 ENSP00000420271
ENST00000495893 ENSP00000420294
ENST00000467570 ENSP00000419089
ENST00000486042 ENSP00000417360
ENST00000484931 ENSP00000418039
ENST00000497171
ENST00000479467 ENSP00000417633
ENST00000466189 ENSP00000417860
ENST00000475729 ENSP00000419899
ENST00000474275 ENSP00000418266
ENST00000472330 ENSP00000420713
ENST00000465896 ENSP00000418377
ENST00000497658 ENSP00000420454
ENST00000481639 ENSP00000417540
ENST00000491258
ENST00000490723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0015629 actin cytoskeleton
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037652
View Gene Order
ENSBTAG00000013938
Not yet available
Pathways
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_169274
Cellular Senescence pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8NDX5
TrEMBL
UniProt Splice Variant
Entrez Gene 80012
UniGene Hs.529592 Hs.738779
RefSeq NM_024947 XM_005247790 XM_005247793 XM_006713757
HUGO HGNC:15682
OMIM
CCDS CCDS46952
HPRD 10149
IMGT
EMBL AC008040 AC023891 AF380154 AF444193 AJ320486 AK022791 AK023029 BC022325 BC070164 BC131772 BX647868 CH471052 EF560717
GenPept AAH22325 AAH70164 AAI31773 AAM46139 AAM51781 BAB14245 BAB14365 CAC86587 CAI46090 EAW78519
RNA Seq Atlas 80012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca