Version 5.4
Bos taurus Gene: MTSS1
Summary
InnateDB Gene IDBG-644178.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTSS1
Gene Name metastasis suppressor protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020407
Encoded Proteins
IDBP-696797
metastasis suppressor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170873:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:16971033-17132800
Strand Forward strand
Band
Transcripts
ENSBTAT00000027195 ENSBTAP00000027195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008093 cytoskeletal adaptor activity
GO:0017124 SH3 domain binding
GO:0042802 identical protein binding
GO:0051015 actin filament binding
Biological Process
GO:0001701 in utero embryonic development
GO:0007009 plasma membrane organization
GO:0007015 actin filament organization
GO:0007165 signal transduction
GO:0010960 magnesium ion homeostasis
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030282 bone mineralization
GO:0032233 positive regulation of actin filament bundle assembly
GO:0034334 adherens junction maintenance
GO:0046847 filopodium assembly
GO:0050680 negative regulation of epithelial cell proliferation
GO:0061333 renal tubule morphogenesis
GO:0071498 cellular response to fluid shear stress
GO:0072001 renal system development
GO:0072102 glomerulus morphogenesis
GO:0072160 nephron tubule epithelial cell differentiation
GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005912 adherens junction
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000170873
View Gene Order
ENSMUSG00000022353
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
hedgehog_glipathway
Hedgehog signaling events mediated by Gli proteins
Cross-References
SwissProt
TrEMBL E1BP52
UniProt Splice Variant
Entrez Gene 523498
UniGene Bt.101925 Bt.111918 Bt.55906
RefSeq NM_001192581 XM_005215371 XM_005215372
HUGO HGNC:20443
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02038147 DAAA02038148 DAAA02038149 DAAA02038150 DAAA02038151
GenPept
RNA Seq Atlas 523498

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca