Version 5.4
Bos taurus Gene: TMEM43
Summary
InnateDB Gene IDBG-646446.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM43
Gene Name transmembrane protein 43
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007360
Encoded Proteins
IDBP-699255
transmembrane protein 43
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170876:
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:58726302-58747763
Strand Reverse strand
Band
Transcripts
ENSBTAT00000009681 ENSBTAP00000009681
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000170876
View Gene Order
ENSMUSG00000030095
View Gene Order
Cross-References
SwissProt
TrEMBL A6QQR5
UniProt Splice Variant
Entrez Gene 404066
UniGene Bt.1609 Bt.96607
RefSeq NM_001102480 XM_005223129
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149964 DAAA02054616 DAAA02054617
GenPept AAI49965
RNA Seq Atlas 404066

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca