Version 5.4
Homo sapiens Gene: GPR133
Summary
InnateDB Gene IDBG-64848.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR133
Gene Name G protein-coupled receptor 133
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111452
Encoded Proteins
IDBP-64850
G protein-coupled receptor 133
IDBP-64854
G protein-coupled receptor 133
IDBP-809487
G protein-coupled receptor 133
IDBP-590576
G protein-coupled receptor 133
IDBP-603719
G protein-coupled receptor 133
IDBP-595583
G protein-coupled receptor 133
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:130953907-131141469
Strand Forward strand
Band q24.33
Transcripts
ENST00000261654 ENSP00000261654
ENST00000376682
ENST00000335486 ENSP00000334127
ENST00000446583 ENSP00000482235
ENST00000541143
ENST00000543826
ENST00000542091 ENSP00000442501
ENST00000535015 ENSP00000444425
ENST00000541937
ENST00000537600
ENST00000544673
ENST00000545900
ENST00000543617 ENSP00000438021
ENST00000536988
ENST00000537489
ENST00000540207
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044017
View Gene Order
ENSBTAG00000013848
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.719239
RefSeq NM_198827
HUGO
OMIM
CCDS CCDS9272
HPRD 17061
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca