Version 5.4
Homo sapiens Gene: MOGAT2
Summary
InnateDB Gene IDBG-64956.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOGAT2
Gene Name monoacylglycerol O-acyltransferase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166391
Encoded Proteins
IDBP-64958
monoacylglycerol O-acyltransferase 2
IDBP-589983
monoacylglycerol O-acyltransferase 2
IDBP-589542
monoacylglycerol O-acyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC 2.3.1.22) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 [PubMed 12621063]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:75717819-75732958
Strand Forward strand
Band q13.5
Transcripts
ENST00000198801 ENSP00000198801
ENST00000525093 ENSP00000436537
ENST00000526712 ENSP00000436283
ENST00000624180
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0016407 acetyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006071 glycerol metabolic process
GO:0006629 lipid metabolic process
GO:0006651 diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0050892 intestinal absorption
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000052396
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa04975
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.288568
RefSeq NM_025098
HUGO
OMIM
CCDS CCDS8240
HPRD 11367
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca