Version 5.4
Homo sapiens Gene: RNF38
Summary
InnateDB Gene IDBG-65110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF38
Gene Name ring finger protein 38
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137075
Encoded Proteins
IDBP-65112
ring finger protein 38
IDBP-65114
ring finger protein 38
IDBP-65116
ring finger protein 38
IDBP-65118
ring finger protein 38
IDBP-65120
ring finger protein 38
IDBP-65122
ring finger protein 38
IDBP-809159
ring finger protein 38
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:36336396-36487548
Strand Reverse strand
Band p13.2
Transcripts
ENST00000377885 ENSP00000367117
ENST00000357058 ENSP00000349566
ENST00000350199 ENSP00000343947
ENST00000259605 ENSP00000259605
ENST00000353739 ENSP00000335239
ENST00000377877 ENSP00000367109
ENST00000491349
ENST00000484621
ENST00000488058
ENST00000611646 ENSP00000483536
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008584 male gonad development
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0036126 sperm flagellum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035696
View Gene Order
ENSBTAG00000005519
Not yet available
Cross-References
SwissProt Q9H0F5
TrEMBL
UniProt Splice Variant
Entrez Gene 152006
UniGene Hs.333503 Hs.609635
RefSeq NM_194329 XM_005251365 XM_005251367 XM_005251368 XM_006716721 NM_022781 NM_194328 NM_194330 NM_194332 XM_005251364 XM_005251366
HUGO HGNC:18052
OMIM 612488
CCDS CCDS6604 CCDS6603
HPRD 11519
IMGT
EMBL AF394047 AK024996 AK093480 AL136817 AL161792 AL354935 BC033786 CH471071
GenPept AAH33786 AAM73697 BAB15050 BAG52726 CAB66751 CAO03540 CAO03541 CAO03553 CAO03554 EAW58305
RNA Seq Atlas 152006

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca