Version 5.4
Homo sapiens Gene: MALL
Summary
InnateDB Gene IDBG-65460.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MALL
Gene Name mal, T-cell differentiation protein-like
Synonyms BENE
Species Homo sapiens
Ensembl Gene ENSG00000144063
Encoded Proteins
IDBP-65462
mal, T-cell differentiation protein-like
IDBP-384456
mal, T-cell differentiation protein-like
IDBP-384459
mal, T-cell differentiation protein-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:110083870-110116566
Strand Reverse strand
Band q13
Transcripts
ENST00000272462 ENSP00000272462
ENST00000427178 ENSP00000400518
ENST00000424988 ENSP00000394792
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0042632 cholesterol homeostasis
Cellular Component
GO:0000139 Golgi membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030136 clathrin-coated vesicle
GO:0045121 membrane raft
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027377
View Gene Order
ENSBTAG00000024091
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.185055 Hs.729715
RefSeq NM_005434
HUGO
OMIM
CCDS CCDS2085
HPRD 15997
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca