Version 5.4
Homo sapiens Gene: LRRC16A
Summary
InnateDB Gene IDBG-66152.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC16A
Gene Name leucine rich repeat containing 16A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000079691
Encoded Proteins
IDBP-66156
leucine rich repeat containing 16A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:25279078-25620530
Strand Forward strand
Band p22.2
Transcripts
ENST00000329474 ENSP00000331983
ENST00000461945
ENST00000497227
ENST00000476458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0032403 protein complex binding
Biological Process
GO:0007015 actin filament organization
GO:0007596 blood coagulation
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0030335 positive regulation of cell migration
GO:0030838 positive regulation of actin filament polymerization
GO:0031529 ruffle organization
GO:0046415 urate metabolic process
GO:0051496 positive regulation of stress fiber assembly
GO:0051638 barbed-end actin filament uncapping
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902745 positive regulation of lamellipodium organization
GO:2000813 negative regulation of barbed-end actin filament capping
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030027 lamellipodium
GO:0031941 filamentous actin
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021338
View Gene Order
ENSBTAG00000016549
Not yet available
Pathways
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.649550
RefSeq NM_001173977 NM_017640 XM_006715138 XM_006715139
HUGO
OMIM
CCDS CCDS54973
HPRD 11285
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca