Homo sapiens Gene: DEFB104A | |||
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Summary | |||
InnateDB Gene | IDBG-6642.6 | ||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||
Gene Symbol | DEFB104A | ||
Gene Name | defensin, beta 104A | ||
Synonyms | |||
Species | Homo sapiens | ||
Ensembl Gene | ENSG00000176782 | ||
Encoded Proteins |
defensin, beta 104A
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Protein Structure | |||
Useful resources | Stemformatics EHFPI ImmGen | ||
Entrez Gene | |||
Summary |
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104B, represents the more telomeric copy. [provided by RefSeq, Jul 2008] Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy. [provided by RefSeq, Jul 2008] |
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Gene Information | |||
Type | Protein coding | ||
Genomic Location | Chromosome 8:7836471-7841242 | ||
Strand | Forward strand | ||
Band | p23.1 | ||
Transcripts |
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Interactions | |||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||
No orthologs found for this gene | |||
Pathways | |||
NETPATH | |||
REACTOME |
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
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KEGG | |||
INOH | |||
PID NCI | |||
Cross-References | |||
SwissProt | Q8WTQ1 | ||
TrEMBL | |||
UniProt Splice Variant | |||
Entrez Gene | 503618 | ||
UniGene | Hs.559507 Hs.742246 | ||
RefSeq | NM_080389 | ||
HUGO | HGNC:18115 | ||
OMIM | |||
CCDS | CCDS34834 | ||
HPRD | |||
IMGT | |||
EMBL | AJ314834 AJ314835 BC100848 BC100849 BC100850 BC100851 | ||
GenPept | AAI00849 AAI00850 AAI00851 AAI00852 CAC85511 CAC85520 | ||
RNA Seq Atlas | 140596 503618 | ||