Version 5.4
Homo sapiens Gene: DNAI2
Summary
InnateDB Gene IDBG-67029.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAI2
Gene Name dynein, axonemal, intermediate chain 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171595
Encoded Proteins
IDBP-67033
dynein, axonemal, intermediate chain 2
IDBP-384021
dynein, axonemal, intermediate chain 2
IDBP-761238
IDBP-757773
IDBP-763021
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:74274247-74314884
Strand Forward strand
Band q25.1
Transcripts
ENST00000311014 ENSP00000308312
ENST00000446837 ENSP00000400252
ENST00000579490 ENSP00000464197
ENST00000582036 ENSP00000461950
ENST00000579312
ENST00000579055 ENSP00000462767
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
GO:0042384 cilium assembly
Cellular Component
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0005930 axoneme
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034706
View Gene Order
ENSBTAG00000016732
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt Q9GZS0
TrEMBL
UniProt Splice Variant
Entrez Gene 64446
UniGene Hs.147472
RefSeq NM_001172810 NM_023036
HUGO HGNC:18744
OMIM 605483
CCDS CCDS11697 CCDS58589
HPRD 12019
IMGT
EMBL AC103809 AF250288 AF253087 AF253088 AF253089 AF253090 AF253091 AF253092 AF253093 AF253094 AF253095 AF253096 AF253097 AF260782 AJ295276 AL137526 BC039582 CH471099
GenPept AAG38000 AAG38489 AAH39582 CAB70790 CAC17464 EAW89146
RNA Seq Atlas 64446

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca