Version 5.4
Homo sapiens Gene: HTR3E
Summary
InnateDB Gene IDBG-67355.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTR3E
Gene Name 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186038
Encoded Proteins
IDBP-67357
5-hydroxytryptamine (serotonin) receptor 3, family member E
IDBP-385849
5-hydroxytryptamine (serotonin) receptor 3, family member E
IDBP-385850
5-hydroxytryptamine (serotonin) receptor 3, family member E
IDBP-385851
5-hydroxytryptamine (serotonin) receptor 3, family member E
IDBP-385852
5-hydroxytryptamine (serotonin) receptor 3, family member E
IDBP-385853
5-hydroxytryptamine (serotonin) receptor 3, family member E
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:184097064-184106995
Strand Forward strand
Band q27.1
Transcripts
ENST00000335304 ENSP00000335511
ENST00000415389 ENSP00000401444
ENST00000425359 ENSP00000401900
ENST00000440596 ENSP00000406050
ENST00000436361 ENSP00000395833
ENST00000431041 ENSP00000391254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.449179
RefSeq NM_001256613 NM_001256614 NM_182589 NM_198313 NM_198314
HUGO
OMIM
CCDS CCDS3251 CCDS58868 CCDS58869 CCDS58870 CCDS58871
HPRD 17122
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca