Version 5.4
Homo sapiens Gene: CD300E
Summary
InnateDB Gene IDBG-67366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD300E
Gene Name CD300e molecule
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186407
Encoded Proteins
IDBP-245294
CD300e molecule
IDBP-384085
CD300e molecule
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 20039296
CD300E functions as an activating receptor capable of regulating the innate immune response in myeloid cells.
Entrez Gene
Summary This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:74609887-74623738
Strand Reverse strand
Band q25.1
Transcripts
ENST00000392619 ENSP00000376395
ENST00000412268 ENSP00000415488
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_147694
DAP12 interactions pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9JDD2
UniProt Splice Variant
Entrez Gene 342510
UniGene Hs.158954 Hs.728058
RefSeq NM_181449
HUGO HGNC:28874
OMIM 609801
CCDS CCDS11702
HPRD 17158
IMGT
EMBL AC064805
GenPept
RNA Seq Atlas 342510

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca