Version 5.4
| Homo sapiens Gene: TAF1D | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-68013.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | TAF1D | ||||||||||||||||||
| Gene Name | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000166012 | ||||||||||||||||||
| Encoded Proteins |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:93729948-93784391 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q21 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Promoter Escape pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase I Transcription pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
SIRT1 negatively regulates rRNA Expression pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Hs.355750 Hs.625539 Hs.689724 Hs.714283 Hs.728881 Hs.738734 Hs.738736 Hs.738740 Hs.741060 Hs.741062 | ||||||||||||||||||
| RefSeq | NM_024116 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS8293 | ||||||||||||||||||
| HPRD | 14679 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||