InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPS9

Summary

InnateDB Gene

IDBG-68296.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS9

Gene Name

ribosomal protein S9

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000170889

Encoded Proteins

IDBP-68298

ribosomal protein S9

IDBP-247057

ribosomal protein S9

IDBP-247059

ribosomal protein S9

IDBP-247061

ribosomal protein S9

IDBP-293471

ribosomal protein S9

IDBP-384659

ribosomal protein S9

IDBP-384663

ribosomal protein S9

IDBP-384665

ribosomal protein S9

IDBP-384675

ribosomal protein S9

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:54200742-54249003

Strand

Forward strand

Band

q13.42

Transcripts

ENST00000302907	ENSP00000302896
ENST00000391753	ENSP00000375633
ENST00000391752	ENSP00000375632
ENST00000391751	ENSP00000375631
ENST00000402367	ENSP00000383937
ENST00000448962	ENSP00000399623
ENST00000436445	ENSP00000406159
ENST00000445961	ENSP00000391823
ENST00000441429	ENSP00000414314
ENST00000484121
ENST00000495002
ENST00000460761

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 130 experimentally validated interaction(s) in this database.

Experimentally validated
Total	130 [view]
Protein-Protein	129 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding
GO:0045182	translation regulator activity

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006417	regulation of translation
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0008284	positive regulation of cell proliferation
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome