Homo sapiens Gene: FUT4
Summary
InnateDB Gene IDBG-68299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUT4
Gene Name fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Synonyms CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1
Species Homo sapiens
Ensembl Gene ENSG00000196371
Encoded Proteins
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:94543840-94549898
Strand Forward strand
Band q21
Transcripts
ENST00000358752 ENSP00000351602
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
GO:0046920 alpha-(1->3)-fucosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0036065 fucosylation
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
GO:0071944 cell periphery
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosphingolipid biosynthesis pathway
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt P22083
TrEMBL
UniProt Splice Variant
Entrez Gene 2526
UniGene Hs.390420
RefSeq NM_002033
HUGO HGNC:4015
OMIM 104230
CCDS CCDS8301
HPRD
IMGT
EMBL AP000943 BC136373 BC136374 CH471065 M58596 M58597 M65030 S65161
GenPept AAA63172 AAA63173 AAA92977 AAB20349 AAI36374 AAI36375 EAW66938
RNA Seq Atlas 2526